Dennis W. Choi, MD, PhD

  • Professor and Chair, Neurology
  • Director, Neurosciences Institute

Board Certification

  • American Board of Psychiatry and Neurology
  • American Board of Clinical Neurophysiology
  • American Board of Electrodiagnostic Medicine


  • Medical School

  • Health Sciences and Technology Program
    Massachusetts Institute of Technology
    and Harvard Medical School
    Boston, MA

  • Graduate School

  • Harvard University
    Boston, MA

  • Residency in Neurology

  • Longwood Area Program
    Harvard University
    Boston, MA

  • Fellowship

  • EEG and Evoked Potentials
    Massachusetts General Hospital
    Boston, MA

Clinical Interests/Expertise

  • General neurology
  • Nervous system injury
  • Disorders of higher cortical function

Biographical Sketch

Dr. Choi is a co-discoverer of the physiological mechanism of action of benzodiazepine drugs, and a pioneer in dissecting processes responsible for pathological neurodegeneration and devising neuroprotective countermeasures. His laboratory identified a key role for NMDA receptor activation and calcium overload in excitotoxicity, and zinc in ischemic brain injury. Later work examined how apoptosis, potassium efflux, and several cell signaling pathways contribute to neuronal death. During the 1990s "Decade of the Brain" his lab was ranked by Science Watch #19 worldwide for highly cited neuroscience publications, and recognized by several awards, including the Wakeman Award, the Conte Award, the Ho-Am Prize, and the Reeve Medal. More recently he has led neuroscience programs in the pharmaceutical industry, and in a private foundation, including those aimed at biomarker development and the early clinical testing of novel candidate therapies for nervous system diseases. He is a founding co-editor of the journal "Neurobiology of Disease", member of the IOM, a fellow of the AAAS, a past President of the Society for Neuroscience, and a past Vice President of the American Neurological Association. He has served on advisory committees to multiple public and private organizations, including HHS, FDA, NIH, and the IOM, and currently serves as Director of the Brain Science Institute at the Korea Institute of Science and Technology.

Dennis W. Choi, MD, PhD

Contact Information

  • Department of Neurology
  • HSC T12, Room 020
  • Stony Brook University Medical Center
  • Stony Brook, NY 11794-8121
  • Academic Office

  • 631-444-2599
  • Appointments

  • 631-444-2599

Ambulatory Care Offices

  • Neurology Associates of Stony Brook
    179 North Belle Mead Avenue
    East Setauket, NY 11733
  • Phone

  • 631-444-2599